See chromothripsis on Wiktionary
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{ "etymology_templates": [ { "args": { "1": "en", "2": "grc", "3": "χρῶμα", "4": "", "5": "colour" }, "expansion": "Ancient Greek χρῶμα (khrôma, “colour”)", "name": "uder" }, { "args": { "1": "en", "2": "chromosome", "3": "chromo(some)" }, "expansion": "English chromo(some)", "name": "cog" } ], "etymology_text": "From Ancient Greek χρῶμα (khrôma, “colour”) (referring to English chromo(some)) + θρίψις (thrípsis, “shattering into pieces”) (from τρίβω (tríbō, “I rub”).", "head_templates": [ { "args": { "1": "-" }, "expansion": "chromothripsis (uncountable)", "name": "en-noun" } ], "lang": "English", "lang_code": "en", "pos": "noun", "related": [ { "word": "chromothriptic" } ], "senses": [ { "categories": [ "English entries with incorrect language header", "English lemmas", "English nouns", "English terms derived from Ancient Greek", "English terms with quotations", "English uncountable nouns", "English undefined derivations", "Pages with 1 entry", "Pages with entries", "Quotation templates to be cleaned", "en:Genetics", "en:Pathology" ], "examples": [ { "ref": "2012, Lauren Pecorino, Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics, page 24:", "text": "But for 2—3% of cancers, particularly bone cancer (up to 25%), recent evidence suggests that a single event of chromothripsis involving one or a few chromosomes leads to multiple gene rearrangements (in some cases tens to hundreds) that can disrupt tumor suppressor genes and/or produce oncogenic fusion genes.", "type": "quote" }, { "ref": "2014, Asfar Azmi, Molecular Diagnostics and Treatment of Pancreatic Cancer, page 113:", "text": "Another new phenomenon described by Stephens et al.[86] is called “chromothripsis”. Chromothripsis describes a massive genomic rearrangement in one or more chromosomes in a single catastrophic event during the cells' history,", "type": "quote" }, { "ref": "2015, Anders M. Lindroth, Yoon Jung Park, Christoph Plass, “Epigenetic Reprogramming in Cancer”, in Alexander Meissner, Jörn Walter, editors, Epigenetic Mechanisms in Cellular Reprogramming, Springer, page 206:", "text": "Some of the characteristics of chromothripsis are oscillating copy number changes, clustering of breakpoints, localized rearrangements involving one or a part of a chromosome, and complex rearrangements.", "type": "quote" } ], "glosses": [ "A multiple of chromosomal rearrangements that is associated with some cancers." ], "links": [ [ "genetics", "genetics" ], [ "pathology", "pathology" ], [ "multiple", "multiple" ], [ "chromosomal", "chromosomal" ], [ "rearrangement", "rearrangement" ], [ "cancer", "cancer" ] ], "raw_glosses": [ "(genetics, pathology) A multiple of chromosomal rearrangements that is associated with some cancers." ], "tags": [ "uncountable" ], "topics": [ "biology", "genetics", "medicine", "natural-sciences", "pathology", "sciences" ], "wikipedia": [ "chromothripsis" ] } ], "word": "chromothripsis" }
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This page is a part of the kaikki.org machine-readable All languages combined dictionary. This dictionary is based on structured data extracted on 2024-12-15 from the enwiktionary dump dated 2024-12-04 using wiktextract (8a39820 and 4401a4c). The data shown on this site has been post-processed and various details (e.g., extra categories) removed, some information disambiguated, and additional data merged from other sources. See the raw data download page for the unprocessed wiktextract data.
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