"chromothripsis" meaning in All languages combined

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  "etymology_text": "From Ancient Greek χρῶμα (khrôma, “colour”) (referring to English chromo(some)) + θρίψις (thrípsis, “shattering into pieces”) (from τρίβω (tríbō, “I rub”).",
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          "ref": "2012, Lauren Pecorino, Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics, page 24",
          "text": "But for 2—3% of cancers, particularly bone cancer (up to 25%), recent evidence suggests that a single event of chromothripsis involving one or a few chromosomes leads to multiple gene rearrangements (in some cases tens to hundreds) that can disrupt tumor suppressor genes and/or produce oncogenic fusion genes.",
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          "ref": "2014, Asfar Azmi, Molecular Diagnostics and Treatment of Pancreatic Cancer, page 113",
          "text": "Another new phenomenon described by Stephens et al.[86] is called “chromothripsis”. Chromothripsis describes a massive genomic rearrangement in one or more chromosomes in a single catastrophic event during the cells' history,",
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          "text": "Some of the characteristics of chromothripsis are oscillating copy number changes, clustering of breakpoints, localized rearrangements involving one or a part of a chromosome, and complex rearrangements.",
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